A recent study suggests that engaging in just 10 minutes of exercise daily may offer protection against cancer. Researchers at Newcastle University have found that brief periods of vigorous physical activity could potentially slow down the advancement of the disease.
The study revealed that intense exercise can rapidly influence the composition of molecules in the blood. These alterations appear to hinder the growth of bowel cancer cells and accelerate the repair of damaged DNA. When bowel cancer cells were exposed to blood enriched with these exercise-induced molecules in a lab setting, significant genetic changes were observed. More than 1,300 genes altered their functions, including those related to DNA repair, energy generation, and cancer cell proliferation.
Published in the International Journal of Cancer, these findings shed light on the potential of physical activity in reducing the risk of bowel cancer. The research highlights that exercise transmits molecular signals through the bloodstream that impact genes responsible for tumor growth and genetic stability.
Dr. Sam Orange, the lead investigator of the study and a senior lecturer in Clinical Exercise Physiology, emphasized the significant impact of exercise on cancer cells. He mentioned that exercise not only benefits healthy tissues but also sends powerful signals through the bloodstream that can directly affect numerous genes in cancer cells. This insight could pave the way for developing therapies that mimic the positive effects of exercise on DNA repair and energy utilization in cells.
The study involved 30 participants aged between 50 and 78, who were overweight or obese but in good health. Each participant underwent a short yet intense cycling assessment lasting about 10 minutes. Blood samples were collected and analyzed for 249 proteins, with 13 proteins showing increased levels post-exercise, including interleukin-6 (IL-6), which aids in DNA repair.
Dr. Orange noted that the results indicate exercise may create an unfavorable environment for cancer cell growth. Even a single workout session can have a positive impact, reinforcing the importance of consistent physical activity for health protection.
The NHS recommends regular exercise to lower the risk of various diseases, including bowel cancer. Physical activity is known to enhance self-esteem, mood, sleep quality, and energy levels while reducing stress. The NHS advises individuals to aim for at least 150 minutes of exercise per week for overall well-being.